Data Downloads

The forms below provide access to the association summary statistics for the DIAGRAM, DIAMANTE and T2DGGI publications starting with the v3 GWAS meta-analysis, as published in Morris et al (2012), through to the latest T2DGGI meta-analyses as published in Suzuki, Hatzikotoulas, Southam, Taylor, Yin, Lorenz, Mandla, et al. (2024).

Stage 1 GWAS: Summary Statistics

Please note that the summary statistics presented in this file have NOT been corrected for a second round of genomic control after meta-analysis. However the P values in the Morris et al paper WERE double GC corrected. There are more details in the PDF below.

The data are made available as a tab-separated table, enclosed in a zip file (about 32Mb). Detailed information about the content of the table is available in this PDF.

The sample size and precision of the data presented should preclude de-identification of any individual subject. However, in downloading these data, you undertake:

not to attempt to de-identify individual subjects.

I agree with the terms above.

SHA1:cc76628428531d978d5aadb5d9e5b73cd0b4cbbe, MD5:b39b008322c22c8fa80a029738cd1155.

Stage 1 GWAS & Stage 2 Metabochip: Summary Statistics

The data are made available as a tab-separated table, enclosed in a zip file (about 3.3Mb). Detailed information about the content of the table is available in this PDF.

The sample size and precision of the data presented should preclude de-identification of any individual subject. However, in downloading these data, you undertake:

not to attempt to de-identify individual subjects.

I agree with the terms above.

SHA1:4e9353d1c8e6399bc3abb6c9fa9bf76d4463c5f7, MD5:7a53d81e4e70e180fc0ca2b243aaeb69.

Stage 1 GWAS & Stage 2 Metabochip: Sex-Specific Summary Statistics

The data are made available as a tab-separated table, enclosed in a zip file (about 7Mb). Detailed information about the content of the table is available in this PDF.

The sample size and precision of the data presented should preclude de-identification of any individual subject. However, in downloading these data, you undertake:

not to attempt to de-identify individual subjects.

I agree with the terms above.

SHA1:8bf2679a087f5418b05a92c3b04a2b2aebcdc82a, MD5:e182d0908085be895b6cb7a066c3198d.

Stage 2 Metabochip: Summary Statistics

The data are made available as a tab-separated table, enclosed in a zip file (about 3.5Mb). Detailed information about the content of the table is available in this PDF.

The sample size and precision of the data presented should preclude de-identification of any individual subject. However, in downloading these data, you undertake:

not to attempt to de-identify individual subjects.

I agree with the terms above.

SHA1:ff90a898d682c7899aba0fa965eb82116e0bb25e, MD5:c59b327be3dcf3b162fc70d8994bc3e1.

Trans-ethnic T2D GWAS meta-analysis

The data are made available as a tab-separated table, enclosed in a zip file (about 46Mb). Detailed information about the content of the table is available in this PDF.

The sample size and precision of the data presented should preclude de-identification of any individual subject. However, in downloading these data, you undertake:

not to attempt to de-identify individual subjects.

I agree with the terms above.

SHA1:md1563f04bf552510953baa62c5dc549b33465096a, MD5:bb41de5f92fc3f62527b64062e2aa0f5.

DIAGRAM Metabochip meta-analysis of T2D: Summary Statistics

Published in Gaulton et al., Nature Genetics, 2015

The data are made available as a tab-separated table, enclosed in a zip file (less than 1Mb). Detailed information about the content of the table is available in this PDF.

The sample size and precision of the data presented should preclude de-identification of any individual subject. However, in downloading these data, you undertake:

not to attempt to de-identify individual subjects.

I agree with the terms above.

SHA1:213f12b6b3fce14e85cb42fbe820e6cf135f6749, MD5:0f75aaf921e97b2fea991bd90c1ca60b.

DIAGRAM Metabochip meta-analysis of T2D: Credible Sets

Published in Gaulton et al., Nature Genetics, 2015

The data are made available as a collection of tab-separated tables, enclosed in a zip file (less than 400Kb). Detailed information about the content of the table is available in this PDF.

The sample size and precision of the data presented should preclude de-identification of any individual subject. However, in downloading these data, you undertake:

not to attempt to de-identify individual subjects.

I agree with the terms above.

SHA1:902a4c1c4b9aca49d84b536accd1dd6b7395aa2b, MD5:db32d3e6853ad318f440e90f7f4058de.

GoT2D and T2D-GENES meta-analysis of T2D: Summary Statistics

Published in Fuchsberger et al (2016)

The data are made available as a tab-separated table enclosed in a zip file (around 145mb). Detailed information about the content of the table is available in this PDF.

The sample size and precision of the data presented should preclude de-identification of any individual subject. However, in downloading these data, you undertake:

not to attempt to de-identify individual subjects.

I agree with the terms above.

SHA1:dfbed9c306b4f11c803b765887b2badaf8f3918a, MD5:1e76dbdf8f0291898332713cf001bc5a.

DIAGRAM 1000G GWAS meta-analysis Stage 1 Summary statistics

Published in Scott et al (2017)

The data are made available as a tab-separated table enclosed in a zip file (around 155 mb). Detailed information about the content of the table is available in this PDF.

The sample size and precision of the data presented should preclude de-identification of any individual subject. However, in downloading these data, you undertake:

not to attempt to de-identify individual subjects.

I agree with the terms above.

SHA1:d48402f1ce501ea5b98335e6e15173bb865bb6f1, MD5:f033ebb95e01afedde7365e4fc6565a2.

DIAGRAM 1000G GWAS meta-analysis with adjustment for BMI Stage 1 Summary statistics

Published in Scott et al (2017)

The data are made available as a tab-separated table enclosed in a zip file (around 138 mb). Detailed information about the content of the table is available in this PDF.

The sample size and precision of the data presented should preclude de-identification of any individual subject. However, in downloading these data, you undertake:

not to attempt to de-identify individual subjects.

I agree with the terms above.

SHA1:73d085832e7c768533fc95f3212e80b82ae4f4bd, MD5:a5e469b5cae0f98bbddac85491a2bfbd.

T2D ExomeChip meta-analysis - European Summary Statistics

Published in Mahajan et al (2018a)

The data are made available as a tab-separated table enclosed in a zip file (around 6 mb). Detailed information about the content of the table is available in this PDF.

The sample size and precision of the data presented should preclude de-identification of any individual subject. However, in downloading these data, you undertake:

not to attempt to de-identify individual subjects.

I agree with the terms above.

SHA1:5c6f457fb9b089d92d4f90f7fe864f187fdd9c1d, MD5:58b5f6a4ef0e62ac938938c56bb64b17.

T2D ExomeChip meta-analysis - Trans-Ethnic Summary Statistics

Published in Mahajan et al (2018a)

The data are made available as a tab-separated table enclosed in a zip file (around 9 mb). Detailed information about the content of the table is available in this PDF.

The sample size and precision of the data presented should preclude de-identification of any individual subject. However, in downloading these data, you undertake:

not to attempt to de-identify individual subjects.

I agree with the terms above.

SHA1:9c1a8dd30599cf38742c64178fbf8dba88cb6ef5, MD5:1506a74af688f032016322e0cc0f59e6.

T2D GWAS meta-analysis - Genetic Credible Sets

Published in Mahajan et al (2018b)

The data are made available as a tab-separated table enclosed in a zip file (around 751K). Detailed information about the content of the table is available in this PDF.

The sample size and precision of the data presented should preclude de-identification of any individual subject. However, in downloading these data, you undertake:

not to attempt to de-identify individual subjects.

I agree with the terms above.

SHA1:a9d633e754a4427e102b99f151249bc49188a94e, MD5:0602214b6e50f4aad4cdd0e26eca9613.

T2D GWAS meta-analysis - Functional Credible Sets

Published in Mahajan et al (2018b)

The data are made available as a tab-separated table enclosed in a zip file (around 488K). Detailed information about the content of the table is available in this PDF.

The sample size and precision of the data presented should preclude de-identification of any individual subject. However, in downloading these data, you undertake:

not to attempt to de-identify individual subjects.

I agree with the terms above.

SHA1:f108d9c62472d1273f9241b2154becf132c61b6d, MD5:8a10a7a0ca6c59cce1546490fd8bf2a4.

T2D GWAS meta-analysis - Unadjusted for BMI

Published in Mahajan et al (2018b)

The data are made available as a tab-separated table enclosed in a zip file (around 347mb). Detailed information about the content of the table is available in this PDF.

The sample size and precision of the data presented should preclude de-identification of any individual subject. However, in downloading these data, you undertake:

not to attempt to de-identify individual subjects.

I agree with the terms above.

SHA1:112e0e789179e15049649151163f5a517ff3ed7e, MD5:53855134fd0862c402cf49ab6233ed6d.

T2D GWAS meta-analysis - Adjusted for BMI

Published in Mahajan et al (2018b)

The data are made available as a tab-separated table enclosed in a zip file (around 314mb). Detailed information about the content of the table is available in this PDF.

The sample size and precision of the data presented should preclude de-identification of any individual subject. However, in downloading these data, you undertake:

not to attempt to de-identify individual subjects.

I agree with the terms above.

SHA1:10d50afe3a9df56a8a0f314b27f8db6db58189d3, MD5:a0855aa81bfe37456660d93819c196db.

T2D GWAS meta-analysis - Summary of T2D associations of HRC variants for only European UK Biobank subjects

Published in in Mahajan et al (2018b)

The data are made available as a tab-separated table enclosed in a zip file (around 164mb). Detailed information about the content of the table is available in this PDF.

The sample size and precision of the data presented should preclude de-identification of any individual subject. However, in downloading these data, you undertake:

not to attempt to de-identify individual subjects.

I agree with the terms above.

SHA1:59cd6aae76fce25edd01c0c06c42b3f36a65402e, MD5:dc15e7222f5f1f8ee0b937cd1ba53590.

T2D GWAS meta-analysis - Summary of T2D associations in females, unadjusted for BMI

Published in Mahajan et al (2018b)

The data are made available as a tab-separated table enclosed in a zip file (around 192mb). Detailed information about the content of the table is available in this PDF.

The sample size and precision of the data presented should preclude de-identification of any individual subject. However, in downloading these data, you undertake:

not to attempt to de-identify individual subjects.

I agree with the terms above.

SHA1:aa0db522c78dc3da76596adbd867908e0b9e5b3b, MD5:530cb9af0b0ed5246d45c7ef74161dd9.

T2D GWAS meta-analysis - Summary of T2D associations in males, unadjusted for BMI

Published in Mahajan et al (2018b)

The data are made available as a tab-separated table enclosed in a zip file (around 190mb). Detailed information about the content of the table is available in this PDF.

The sample size and precision of the data presented should preclude de-identification of any individual subject. However, in downloading these data, you undertake:

not to attempt to de-identify individual subjects.

I agree with the terms above.

SHA1:b7638707f0c5302442a7faeff4bf88a81610fe21, MD5:a1999595056edf6971ede4ea7473951b.

T2D GWAS meta-analysis - Summary of T2D associations, unadjusted for BMI and without UK Biobank subjects

Published in Mahajan et al (2018b)

The data are made available as a tab-separated table enclosed in a zip file (around 229mb). Detailed information about the content of the table is available in this PDF.

The sample size and precision of the data presented should preclude de-identification of any individual subject. However, in downloading these data, you undertake:

not to attempt to de-identify individual subjects.

I agree with the terms above.

SHA1:46a145bdcb73ad4321af004aeacf4cdf367ef98b, MD5:e51f384924efced3acdc41dce9127162.

T2D GWAS meta-analysis - Summary of T2D associations in females, unadjusted for BMI and without UK Biobank subjects

Published in Mahajan et al (2018b)

The data are made available as a tab-separated table enclosed in a zip file (around 177mb). Detailed information about the content of the table is available in this PDF.

The sample size and precision of the data presented should preclude de-identification of any individual subject. However, in downloading these data, you undertake:

not to attempt to de-identify individual subjects.

I agree with the terms above.

SHA1:e550f8ce68fabe13c249d1bfad610bb4b4fccd5d, MD5:6cfb5caeb97ba47f737405ae2189cd7a.

T2D GWAS meta-analysis - Summary of T2D associations in males, unadjusted for BMI and without UK Biobank subjects

Published in Mahajan et al (2018b)

The data are made available as a tab-separated table enclosed in a zip file (around 175mb). Detailed information about the content of the table is available in this PDF.

The sample size and precision of the data presented should preclude de-identification of any individual subject. However, in downloading these data, you undertake:

not to attempt to de-identify individual subjects.

I agree with the terms above.

SHA1:d2b2b0c8a8c62ec60aaae6d975e6d3d52fc5c7e4, MD5:f761612ca56fba2513293b6b4becd225.

Multi-ancestry GWAS meta-analysis summary statistics

Published in Mahajan et al (2022)

The data are made available as a tab-separated table enclosed in a zip file (around 465mb). Detailed information about the content of the table is available in this PDF .

The sample size and precision of the data presented should preclude de-identification of any individual subject. However, in downloading these data, you undertake:

not to attempt to de-identify individual subjects.

I agree with the terms above.

SHA1:e97c0c0174526eacba0b6cb77a504094777e7a99, MD5:aae1e6d96d929ebf22a392f5ed346694.

Multi-ancestry GWAS meta-analysis Fine Mapping and Credible Set data

Published in Mahajan et al (2022)

The fine mapping and credible set data can be downloaded as a single Zip file using the download button below. Detailed information about the contents and format of these files is available in this PDF .

Check box to download.

SHA1:aa2d221d737606cb6250100fce8351d996f0e9bb, MD5:629e9d110f1feb48b909ef4bee01eecd.

The following are the ancestry specific analyses but please note that African and Hispanic ancestry-specific summary statistics will be made available on acceptance of manuscripts describing the results of these analyses

Ancestry specific GWAS meta-analysis summary statistics: South Asian

Published in Mahajan et al (2022)

The data are made available as a tab-separated table enclosed in a zip file (around 196mb). Detailed information about the content of the table is available in this PDF.

The sample size and precision of the data presented should preclude de-identification of any individual subject. However, in downloading these data, you undertake:

not to attempt to de-identify individual subjects.

I agree with the terms above.

SHA1:363c84ec14d3b84c060ecd42b002485f010df22c, MD5:457b875fb9f205b60dfebb4787039505.

Ancestry specific GWAS meta-analysis summary statistics: East Asian

Published in Mahajan et al (2022)

The data are made available as a tab-separated table enclosed in a zip file (around 169mb). Detailed information about the content of the table is available in this PDF.

The sample size and precision of the data presented should preclude de-identification of any individual subject. However, in downloading these data, you undertake:

not to attempt to de-identify individual subjects.

I agree with the terms above.

SHA1:04ec95f945170f2f65289b26b45157e8144f0c7f, MD5:fa10e0c4b33f9e08277f7d919cfb3938.

Ancestry specific GWAS meta-analysis summary statistics: European

Published in Mahajan et al (2022)

The data are made available as a tab-separated table enclosed in a zip file (around 191mb). Detailed information about the content of the table is available in this PDF.

The sample size and precision of the data presented should preclude de-identification of any individual subject. However, in downloading these data, you undertake:

not to attempt to de-identify individual subjects.

I agree with the terms above.

SHA1:a60926183b5d8d66f8dfcd207e3e4bf94e3eb893, MD5:157743a89874b91ed078270c97e22f5b.

The following are the summary statistics from the 2023 T2DGGI paper Ken Suzuki, Konstantinos Hatzikotoulas, Lorraine Southam, Henry J. Taylor, Xianyong Yin, Kim M. Lorenz, Ravi Mandla, et al. Nature. (2024)

T2DGGI GWAS all ancestry meta-analysis summary statistics

Published in Ken Suzuki, Konstantinos Hatzikotoulas, Lorraine Southam, Henry J. Taylor, Xianyong Yin, Kim M. Lorenz, Ravi Mandla, et al. Nature. (2024)

The data are made available as a tab-separated table enclosed in a zip file (around 680mb). Detailed information about the content of the table is available in this Document.

The sample size and precision of the data presented should preclude de-identification of any individual subject. However, in downloading these data, you undertake:

not to attempt to de-identify individual subjects.

I agree with the terms above.

SHA1:1a67558378ac54949d582d3af6a32115f78added, MD5:21503cf0e292e5c2c14c51d74b0aeeea.

The following are the ancestry specific summary statistics from the 2023 T2DGGI paper Ken Suzuki, Konstantinos Hatzikotoulas, Lorraine Southam, Henry J. Taylor, Xianyong Yin, Kim M. Lorenz, Ravi Mandla, et al. Nature. (2024)

T2DGGI GWAS AFA ancestry meta-analysis summary statistics

Published in Ken Suzuki, Konstantinos Hatzikotoulas, Lorraine Southam, Henry J. Taylor, Xianyong Yin, Kim M. Lorenz, Ravi Mandla, et al. Nature. (2024)

The data are made available as a tab-separated table enclosed in a zip file (around 360mb). Detailed information about the content of the table is available in this Document.

The sample size and precision of the data presented should preclude de-identification of any individual subject. However, in downloading these data, you undertake:

not to attempt to de-identify individual subjects.

I agree with the terms above.

SHA1:b2123c35efe03a25db50067435b97a1c66b8a7f5, MD5:e7540a20adf5aebdeafef26539239bdd.

T2DGGI GWAS EAS ancestry meta-analysis summary statistics

Published in Ken Suzuki, Konstantinos Hatzikotoulas, Lorraine Southam, Henry J. Taylor, Xianyong Yin, Kim M. Lorenz, Ravi Mandla, et al. Nature. (2024)

The data are made available as a tab-separated table enclosed in a zip file (around 320mb). Detailed information about the content of the table is available in this Document.

The sample size and precision of the data presented should preclude de-identification of any individual subject. However, in downloading these data, you undertake:

not to attempt to de-identify individual subjects.

I agree with the terms above.

SHA1:9f65d8f3c20ac0a39d004f6ab7c3ffdfd760b914, MD5:4f18dd6bcc9b7dfd0c54f2dea3bf2a09.

T2DGGI GWAS EUR ancestry meta-analysis summary statistics

Published in Ken Suzuki, Konstantinos Hatzikotoulas, Lorraine Southam, Henry J. Taylor, Xianyong Yin, Kim M. Lorenz, Ravi Mandla, et al. Nature. (2024)

The data are made available as a tab-separated table enclosed in a zip file (around 365mb). Detailed information about the content of the table is available in this Document.

The sample size and precision of the data presented should preclude de-identification of any individual subject. However, in downloading these data, you undertake:

not to attempt to de-identify individual subjects.

I agree with the terms above.

SHA1:6122209fff7c3f19a95d024c0ff75f0fe029d65f, MD5:bc7402c2c68b94be1ac8b42fa7e05431.

T2DGGI GWAS HIS ancestry meta-analysis summary statistics

Published in Ken Suzuki, Konstantinos Hatzikotoulas, Lorraine Southam, Henry J. Taylor, Xianyong Yin, Kim M. Lorenz, Ravi Mandla, et al. Nature. (2024)

The data are made available as a tab-separated table enclosed in a zip file (around 350mb). Detailed information about the content of the table is available in this Document.

The sample size and precision of the data presented should preclude de-identification of any individual subject. However, in downloading these data, you undertake:

not to attempt to de-identify individual subjects.

I agree with the terms above.

SHA1:a500e84717c5cd0505b93e00156bba547ddeda58, MD5:471476d3eb33167514cbccaae827db05.

T2DGGI GWAS SAS ancestry meta-analysis summary statistics

Published in Ken Suzuki, Konstantinos Hatzikotoulas, Lorraine Southam, Henry J. Taylor, Xianyong Yin, Kim M. Lorenz, Ravi Mandla, et al. Nature. (2024)

The data are made available as a tab-separated table enclosed in a zip file (around 270mb). Detailed information about the content of the table is available in this Document.

The sample size and precision of the data presented should preclude de-identification of any individual subject. However, in downloading these data, you undertake:

not to attempt to de-identify individual subjects.

I agree with the terms above.

SHA1:b86001da7321f052f7369cd622b38841494fc462, MD5:76cc1f6af383be0530894dad1a489a82.

Please refer any queries to